The plus and minus signs (+ and ?) are mathematical symbols used to represent the notions of positive and negative as well as the operations of addition and subtraction. Their use has been extended to many other meanings, more or less analogous. Plus and minus are Latin terms meaning "more" and "less", respectively. . A double plus (++) is sometimes used to denote double check.

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Is your model a right-handed helix or a left-handed helix? If you hold it pointing away from you and it twists clockwise moving away, it is right-handed, otherwise it is left-handed. These models are The helix of normal DNA is right-handed.

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